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Venlafaxine HCl extended-release capsules is indicated for the treatment of depression. Venlafaxine extended-release (XR) is indicated for the treatment of Generalized Anxiety Disorder (GAD). Venlafaxine may also have clinical utility in a number of other disorders including obsessive compulsive disorder, panic disorder, eating disorders, substance abuse, headaches, hot flashes, and chronic pain (including neuropathic pain).